Acyclovir is acyclic purine nucleoside analogue active against herpes
simplex virus, varicella zoster, Epstein-Barr virus and
cytomegalovirus. In the cell, undergo phosphorylation acyclovir
acyclovir triphosphate into an active form that inhibit the herpes
simplex virus DNA polymerase and viral DNA replication, thereby
preventing viral DNA synthesis without affecting normal cell processes.
Acyclovir Pharmacology
Acyclovir is an antiviral agent highly active in vitro against herpes
simplex virus (HSV) types I and II, and varicella zoster virus. Upon
entry into the infected cell, the phosphorylated form of the active
compound Acyclovir Acyclovir trifosfate. The initial phase of the
process depends on the enzyme thymidine kinase viral-coded. Acyclovir
trifosfate act as inhibitors and as a false substrate for the
herpes-specified DNA polymerase which prevents viral DNA synthesis
without affecting normal cellular processes.
Treatment of herpes simplex virus infections of the skin and mucous
membranes including initial and recurrent genital herpes / recurrent,
herpes zoster (shingles / shingles / shingles). Preventing recurrence of
herpes simplex infections in patients with strong immune systems.
Preventing herpes simplex infection in patients with poor immune
systems.
Another acyclovir pharmacology is a treatment of herpes simplex virus
infections of the skin and mucous membranes including initial and
recurrent genital herpes / recurrent, herpes zoster (shingles / shingles
/ shingles); preventing recurrence of herpes simplex infections in
patients with strong immune systems; preventing herpes simplex infection
in patients with poor immune systems.
Acyclovir Indication
Acyclovir indication such as treatment of herpes simplex virus on the
skin and mucus membranes, including initial and recurrent genital
herpes; treatment of herpes zoster and varicella infections; treatment
of infections caused by the herpes simplex of the skin and mucous
membranes including initial and recurrent genital herpes, herpes simplex
infection prevention in immuno-compromised patients; treatment of
herpes zoster infection.
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